Migraines are much more than just a headache. They are a chronic neurological disorder that significantly impacts the quality of life of millions of people worldwide. While they may occur occasionally, many people live with frequent and disabling episodes. At Homestead Associates in Research, located in Homestead, Florida, we are dedicated to advancing knowledge of this condition through migraine clinical trials, offering patients the opportunity to access new therapies and treatments.
Alzheimer’s Disease is a progressive neurodegenerative condition that affects millions of people worldwide. At Homestead Associates in Research, we are committed to conducting Alzheimer’s clinical trials aimed at finding new treatments to improve patient outcomes and quality of life.
Liver cirrhosis is a chronic liver condition that causes progressive damage to liver tissue, impairing its function. At Homestead Associates in Research, we offer access to clinical trials for liver cirrhosis that may provide new treatment alternatives for patients living with this disease.
COPD (Chronic Obstructive Pulmonary Disease) is a serious and progressive lung condition that makes it difficult to breathe by limiting the airflow to the lungs. At Homestead Associates in Research, located in Homestead, Florida, we provide clear and reliable information about this disease, as well as the opportunity to participate in specialized clinical trials. These studies aim to improve current treatments and, in many cases, offer new therapeutic alternatives for those living with COPD. This blog offers essential details about its symptoms, diagnosis, treatment, risk factors, and how you can contribute to advancing medicine through clinical research.
Myasthenia Gravis is a chronic neuromuscular disease that causes weakness in voluntary muscles. It affects the communication between nerves and muscles, making daily tasks like chewing, speaking, or even breathing difficult. At Homestead Associates in Research, we conduct clinical trials for Myasthenia Gravis, providing patients with new treatment alternatives under expert medical supervision.
Learn the symptoms, causes, and treatment of CIDP and how to join clinical trials at Homestead Associates in Research.
Parkinson’s Disease: Symptoms, Treatments, and How to Participate in Clinical Trials
Parkinson’s disease is a chronic, progressive neurodegenerative disorder that primarily affects movement, but can also lead to a range of non-motor symptoms. It is caused by the gradual loss of dopamine-producing nerve cells in the brain. Dopamine is a chemical messenger essential for coordinating smooth and balanced muscle activity. While there is currently no cure for Parkinson’s, treatments are available to help manage the symptoms and improve quality of life.
At Homestead Associates in Research, we are committed to advancing innovative treatments through Parkinson’s clinical trials, giving patients access to new therapies while contributing to the future of medical science.
What is Parkinson’s Disease?
Parkinson’s disease is a neurodegenerative disorder that affects an area of the brain called the substantia nigra, where dopamine is produced. As these cells begin to die off, dopamine levels drop, disrupting communication between brain regions that control movement.
Although Parkinson’s is more common in older adults, it can also appear in younger people, in what is known as early-onset Parkinson’s disease. It affects both men and women, though it tends to be more common in men.
Symptoms of Parkinson´s Disease
Parkinson’s symptoms can vary greatly from person to person. They often begin gradually and worsen over time. Symptoms are usually divided into two main categories: motor and non-motor.
Main motor symptoms
-Tremors, usually starting in the hands, arms, legs, jaw, or face while at rest.
-Bradykinesia (slowness of movement), which makes everyday tasks more difficult and time-consuming.
-Muscle stiffness, causing discomfort and reduced range of motion.
-Postural instability, increasing the risk of falls.
-Gait disturbances, including shuffling steps and a stooped posture.
Non-motor symptoms
-Sleep disorders, such as insomnia or acting out dreams.
-Loss of smell (anosmia), sometimes appearing years before motor symptoms.
-Digestive problems, including constipation.
-Mood changes, such as depression, anxiety, or apathy.
-Cognitive challenges, especially in advanced stages.
-Chronic fatigue and low energy levels.
-Early recognition of symptoms can lead to earlier diagnosis and more effective management of the disease.
Diagnosing Parkinson’s Disease
There is currently no single test to definitively diagnose Parkinson’s disease. Instead, diagnosis is based on a detailed medical history, a neurological exam, and the presence of characteristic symptoms.
In some cases, imaging tests like MRI or PET scans may be used to rule out other conditions that mimic Parkinson’s symptoms. A positive response to Parkinson’s medications can also help confirm the diagnosis.
Getting an early diagnosis allows patients to begin treatment sooner, potentially slowing symptom progression and improving quality of life.
Parkinson’s Disease Treatments
Although there is no cure for Parkinson’s disease, several treatment options can significantly reduce symptoms and enhance patients’ daily functioning:
-Dopaminergic medications, such as levodopa and dopamine agonists, help replenish or mimic dopamine in the brain.
-MAO-B inhibitors and other medications that extend the effects of dopamine.
-Supportive therapies like physical therapy, occupational therapy, and speech therapy to maintain mobility, independence, and communication abilities.
-Deep brain stimulation (DBS), a surgical procedure where electrodes are implanted in the brain to regulate abnormal impulses and reduce motor symptoms.
-Psychological support, patient education, and caregiver involvement are also key components of a comprehensive care plan.
Causes and Risk Factors
The exact cause of Parkinson’s disease remains unknown, but researchers believe it involves a complex combination of genetic and environmental factors.
Common risk factors include:
-Age (most cases occur after age 60)
-Male gender
-Family history of Parkinson’s
-Long-term exposure to pesticides or other toxins
-History of head trauma
Understanding your risk factors can help with early detection and preventive care.
Who is Affected by Parkinson’s?
It is estimated that more than 10 million people worldwide are living with Parkinson’s disease. In the United States, about 90,000 people are diagnosed each year. As the global population continues to age, these numbers are expected to rise significantly in the coming decades.
Parkinson’s affects individuals physically, emotionally, and socially, making timely diagnosis and care essential for maintaining a better quality of life.
Parkinson’s Clinical Trials at Homestead Associates
At Homestead Associates in Research, we conduct clinical trials for Parkinson’s with innovative treatments that could make a difference. Participating in our studies not only contributes to medical advancement but also provides access to modern therapeutic options and specialized supervision.
If you or a loved one has been diagnosed with this condition, you can participate in our clinical trials and be part of the change in medical research..
Multiple sclerosis (MS) is a chronic disease of the central nervous system that affects the brain and spinal cord. It is an autoimmune disorder in which the immune system attacks the myelin—the protective covering of nerve fibers—disrupting communication between the brain and the rest of the body.
Agitation in Dementia: Causes, Symptoms and How to Manage It
Agitation in dementia is a common condition affecting many older adults, especially those diagnosed with Alzheimer’s. It can manifest as irritability, sleep disturbances, aggression, or pacing, and presents challenges for both caregivers and healthcare providers. Next, we’ll explore the causes, symptoms, and practical strategies for effectively managing agitation in people with dementia.
What is agitation in dementia patients?
Agitation refers to behaviors such as:
– Verbal or physical aggression
– Restlessness or repetitive movements
– Confusion and disorientation
– Sleep disturbances
These dementia symptoms often occur in the middle or late stages of the disease. Up to 80% of patients may experience some form of agitation.
Common causes of agitation in older adults
Key causes of agitation in older adults include:
– Physical changes in the brain
– Pain or physical discomfort
– Unfamiliar or noisy environments
– Communication difficulties
– Poor sleep patterns
– Infections
Agitation often stems from emotional distress or unmet needs. A calm and understanding approach is essential.
Managing agitation in dementia patients
Effective agitation management involves identifying the cause and using appropriate strategies.
Non-pharmacological approaches
Maintain a calm, clutter-free environment
Use familiar objects and daily routines
Offer soft music, gentle touch, or reading
Avoid arguing or confronting during episodes
Care strategies for people with dementia and agitation
Limit caffeine and sugar intake
Keep noise levels low and surroundings organized
Encourage independence in simple tasks
Monitor for infections or physical pain
Seek professional guidance when needed
Responsible use of medications
Medication should be considered only when necessary and under medical supervision. Avoid anticholinergic drugs that can worsen agitation.
Who is at risk?
Agitation in dementia most commonly affects:
– Adults over 65
– Individuals with family history of dementia
– People with diabetes or hypertension
– Those with unhealthy lifestyles (alcohol, smoking)
– Latino and African-American communities
Understanding Agitation in People with Dementia
Agitation is a common symptom in people with dementia, affecting nearly 60% of patients. When associated with wandering, this percentage can rise to 80%. Agitation and aggression are two of the most frequent behavioral disorders in this context, significantly impacting both the patient and their caregivers.
Support for caregivers
Supporting someone with agitation and dementia can be physically and emotionally demanding. Caregivers should seek guidance, rest, and emotional support to provide the best care possible.
Research That Transforms Lives: Homestead Associates’ Commitment to Dementia with Agitation
At Homestead Associates in Research, Inc., we are firmly committed to improving the quality of life for patients living with dementia with agitation. Through carefully designed clinical trials, our team researches new therapies aimed at reducing agitation symptoms and providing relief for both patients and their caregivers. Each study we conduct is an opportunity to advance medical knowledge and bring hope to families facing this challenging condition. Participating in our trials not only provides access to emerging treatments, but also contributes to the development of more humane and effective solutions for this reality.
Psychosis with Dementia is a condition that combines cognitive decline with psychotic symptoms, such as hallucinations and delusions. This combination poses a significant challenge for those affected and their caregivers.
